Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 19/20 | 0.73 |
| ▸ | PDE4A | P27815 | 18/20 | 0.73 |
| ▸ | PDE4C | Q08493 | 18/20 | 0.73 |
| ▸ | PDE4D | Q08499 | 18/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6171292 | 1.00 | PDE4B (0.73) | PDE4BPDE4APDE4CPDE4DPOLB | |
| SCHEMBL6175086 | 1.00 | PDE4B (0.73) | PDE4BPDE4APDE4CPDE4DPOLB | |
| SCHEMBL7177924 | 0.89 | PDE4A (0.68) | PDE4BPDE4APDE4CPDE4DPOLB | |
| SCHEMBL7375528 | 0.89 | PDE4A (0.78) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8646199 | 0.88 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6170468 | 0.88 | PDE4B (0.73) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6170471 | 0.88 | PDE4B (0.73) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7793438 | 0.88 | PDE4A (0.76) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7793227 | 0.88 | PDE4A (0.76) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6171409 | 0.88 | PDE4B (0.73) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794774-B1 | 4,4-(DISUBSTITUTED)CYCLOHEXAN-1-OLS MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2005-10-12 | — | — | EP | disclosed |
| US-5977122-A | 4,4-(disubstituted)cyclohexan-1-ols monomers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| US-5891883-A | 4,4-(disubstituted)cyclohexan-1-ols monomers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-04-06 | — | — | US | disclosed |
| US-5861421-A | 4,4-(disubstituted) cyclohexan-1-one monomers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-01-19 | — | — | US | disclosed |
| EP-0828493-A4 | 4.4-(DISUBSTITUTED)CYCLOHEXAN-1-OLS-MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1998-09-02 | — | — | EP | disclosed |
| US-5777176-A | 4,4-(disubstituted)cyclohexan-1-ol dimers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0828493-A1 | 4.4-(DISUBSTITUTED)CYCLOHEXAN-1-OLS-MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038150-A1 | 4.4-(DISUBSTITUTED)CYCLOHEXAN-1-OLS-MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-12-05 | — | — | WO | disclosed |
| WO-1996019988-A1 | 4,4-(DISUBSTITUTED)CYCLOHEXAN-1-OLS MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-07-04 | — | — | WO | disclosed |