Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28255694 | 0.90 | KCNA5 (0.50) | KCNA5NQO2KDM4ACTSKPOLB | |
| SCHEMBL28210982 | 0.87 | KDM4A (0.47) | KCNA5NQO2KDM4ACTSKPOLB | |
| SCHEMBL6095753 | 0.81 | MEN1 (0.47) | KCNA5NQO2KDM4ACTSKPOLB | |
| SCHEMBL10476446 | 0.80 | CLCN2 (0.41) | POLBCLCN2CA12HTTCA9 | |
| SCHEMBL1808874 | 0.80 | KCNA5 (0.56) | KCNA5NQO2KDM4ACTSKATM | |
| SCHEMBL8240426 | 0.80 | KCNA5 (0.50) | KCNA5NQO2KDM4ACTSKPOLB | |
| SCHEMBL6290025 | 0.79 | KCNA5 (0.50) | KCNA5NQO2KDM4ACTSKPOLB | |
| SCHEMBL1965799 | 0.79 | KCNA5 (0.50) | KCNA5NQO2KDM4ACTSKPOLB | |
| SCHEMBL26659635 | 0.79 | KCNA5 (0.55) | KCNA5NQO2KDM4ACTSKATM | |
| Water SCHEMBL30667520 | 0.76 | KCNA5 (0.53) | KCNA5NQO2KDM4ACTSKSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549613-A1 | SULFONAMIDES HAVING ANTIANGIOGENIC AND ANTICANCER ACTIVITY | Abbott Laboratories (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004033419-A1 | SULFONAMIDES HAVING ANTIANGIOGENIC AND ANTICANCER ACTIVITY | ABBOTT LABORATORIES (US) | 2004-04-22 | — | — | WO | disclosed |