Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 10/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6171160 | 0.94 | ADA (0.44) | ADAPTGER4PTGER3PTGER2LPAR1 | |
| SCHEMBL6169457 | 0.87 | ADA (0.49) | ADALPAR1TBXAS1 | |
| SCHEMBL6169584 | 0.86 | ADA (0.52) | ADA | |
| SCHEMBL6173997 | 0.86 | ADA (0.42) | ADAPTGER4PTGER3PTGER2LPAR1 | |
| SCHEMBL6171261 | 0.86 | ADA (0.44) | ADALPAR1PTGER1 | |
| SCHEMBL6133321 | 0.86 | ADA (0.42) | ADAPTGER4PTGER3PTGER2LPAR1 | |
| SCHEMBL6172589 | 0.86 | ADA (0.49) | ADALPAR1PTGER1 | |
| SCHEMBL6170057 | 0.84 | ADA (0.51) | ADA | |
| SCHEMBL6173056 | 0.84 | ADA (0.44) | ADAPTGER4PTGER3PTGER2LPAR1 | |
| SCHEMBL6172528 | 0.84 | ADA (0.42) | ADALPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098885-B9 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-05-18 | — | — | EP | disclosed |
| EP-1098885-B1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-11-17 | — | — | EP | disclosed |
| US-6359145-B1 | ADENOSINE DEAMINASE INHIBITOR; ANTIINFLAMMATORY AGENTS; IMMUNOSUPPRESSANT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |