Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 14/20 | 0.64 |
| ▸ | MC3R | P41968 | 2/20 | 0.64 |
| ▸ | MC1R | Q01726 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MC5R | P33032 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | UGCG | Q16739 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5887751 | 0.92 | MC4R (0.72) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL5887749 | 0.92 | MC4R (0.72) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL5888408 | 0.92 | MC4R (0.72) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL6177788 | 0.91 | MC4R (0.62) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL6175421 | 0.91 | MC4R (0.62) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL3142002 | 0.87 | MC4R (0.74) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL5887720 | 0.86 | MC4R (0.72) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL5887882 | 0.86 | MC4R (0.72) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL5887718 | 0.86 | MC4R (0.72) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL5887836 | 0.85 | MC4R (0.70) | MC4RMC3RMC1RALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499588-A1 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2005-01-26 | — | — | EP | claimed |
| WO-2003093234-A1 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2003-11-13 | — | — | WO | claimed |