Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.80 |
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985961 | 0.93 | F2 (0.80) | F2ESR1ESR2 | |
| SCHEMBL7983358 | 0.92 | F2 (0.79) | F2ESR1ESR2 | |
| SCHEMBL6172241 | 0.90 | F2 (0.66) | F2 | |
| SCHEMBL7452488 | 0.89 | F2 (1.00) | F2ESR1ESR2 | |
| SCHEMBL7986006 | 0.89 | F2 (0.89) | F2ESR1ESR2 | |
| SCHEMBL6594996 | 0.88 | F2 (1.00) | F2ESR1ESR2 | |
| SCHEMBL7989322 | 0.88 | F2 (0.81) | F2ESR1ESR2 | |
| SCHEMBL7444827 | 0.87 | F2 (0.80) | F2ESR1ESR2 | |
| SCHEMBL7990712 | 0.87 | F2 (0.80) | F2ESR1ESR2 | |
| SCHEMBL6173229 | 0.87 | F2 (0.87) | F2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027051-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2005-01-05 | — | — | EP | disclosed |
| US-6391901-B1 | Thrombin inhibitors | ELI LILLY AND COMPANY | 2002-05-21 | — | — | US | disclosed |