Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 19/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172752 | 0.90 | IGF1R (0.54) | IGF1R | |
| SCHEMBL6174747 | 0.88 | IGF1R (0.57) | IGF1R | |
| SCHEMBL6174982 | 0.87 | IGF1R (0.56) | IGF1R | |
| SCHEMBL6173969 | 0.85 | IGF1R (0.55) | IGF1R | |
| SCHEMBL6173826 | 0.84 | IGF1R (0.53) | IGF1R | |
| SCHEMBL6175883 | 0.84 | IGF1R (0.51) | IGF1R | |
| SCHEMBL6174759 | 0.84 | IGF1R (0.54) | IGF1R | |
| SCHEMBL6173795 | 0.83 | IGF1R (0.67) | IGF1R | |
| SCHEMBL6177581 | 0.82 | IGF1R (0.50) | IGF1R | |
| SCHEMBL2938287 | 0.82 | IGF1R (0.80) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |