Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 18/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172608 | 0.83 | IGF1R (0.46) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL2942884 | 0.83 | IGF1R (0.50) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL2936903 | 0.81 | IGF1R (0.72) | IGF1R | |
| SCHEMBL2934697 | 0.80 | IGF1R (0.57) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL12603226 | 0.80 | AR (0.47) | IGF1RPPARGPPARDPPARAAR | |
| SCHEMBL2940116 | 0.79 | IGF1R (0.69) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL2934260 | 0.79 | IGF1R (0.50) | IGF1RPPARGPPARDPPARAAR | |
| SCHEMBL12873241 | 0.79 | SLC6A2 (0.46) | IGF1RPPARGPPARDPPARAAR | |
| SCHEMBL2942384 | 0.79 | IGF1R (0.50) | IGF1RPPARGPPARDPPARAAR | |
| SCHEMBL2941310 | 0.79 | IGF1R (0.50) | IGF1RPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |