Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 19/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2935176 | 0.87 | IGF1R (0.75) | IGF1R | |
| SCHEMBL2941516 | 0.81 | IGF1R (0.70) | IGF1R | |
| SCHEMBL6221882 | 0.80 | IGF1R (0.58) | IGF1R | |
| SCHEMBL2935582 | 0.76 | IGF1R (0.79) | IGF1R | |
| SCHEMBL2980303 | 0.76 | IGF1R (0.82) | IGF1R | |
| SCHEMBL2996026 | 0.76 | IGF1R (0.81) | IGF1R | |
| SCHEMBL3734038 | 0.76 | IGF1R (0.72) | IGF1R | |
| SCHEMBL4101203 | 0.76 | IGF1R (0.78) | IGF1R | |
| SCHEMBL4033708 | 0.76 | IGF1R (0.78) | IGF1R | |
| SCHEMBL2939085 | 0.76 | IGF1R (1.00) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | claimed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | claimed |