⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3627661 | 0.80 | — | — | |
| SCHEMBL7520516 | 0.79 | — | — | |
| SCHEMBL5872362 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL29001088 | 0.77 | — | — | |
| SCHEMBL6313430 | 0.77 | SLC1A2 (0.46) | — | |
| SCHEMBL10522583 | 0.77 | GAA (0.41) | — | |
| SCHEMBL20521609 | 0.75 | SLC7A5 (0.50) | — | |
| SCHEMBL7917249 | 0.75 | GRIK1 (0.47) | — | |
| SCHEMBL13278949 | 0.73 | GRIK1 (0.49) | — | |
| Ammonia Solution, Strong SCHEMBL8683464 | 0.73 | GRIK1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210332006-A1 | CARBON DIOXIDE-REVERSIBLY-PROTECTED CHAIN EXTENSION-CROSSLINKING AGENT AND PREPARATION METHOD AND USE THEREOF | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2021-10-28 | — | — | US | claimed |
| EP-3862344-A1 | CARBON DIOXIDE REVERSIBLY PROTECTED CHAIN-EXTENDING CROSS-LINKING AGENT, PREPARATION METHOD THEREFOR AND USE THEREOF | Changchun Institute Of Applied Chemistry Chinese Academy Of Sciences (CN) | 2021-08-11 | — | — | EP | claimed |
| US-11401238-B2 | Carbon dioxide-reversibly-protected chain extension-crosslinking agent and preparation method and use thereof | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2022-08-02 | — | — | US | disclosed |
| US-20210332006-A1 | CARBON DIOXIDE-REVERSIBLY-PROTECTED CHAIN EXTENSION-CROSSLINKING AGENT AND PREPARATION METHOD AND USE THEREOF | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2021-10-28 | — | — | US | disclosed |
| EP-3862344-A1 | CARBON DIOXIDE REVERSIBLY PROTECTED CHAIN-EXTENDING CROSS-LINKING AGENT, PREPARATION METHOD THEREFOR AND USE THEREOF | Changchun Institute Of Applied Chemistry Chinese Academy Of Sciences (CN) | 2021-08-11 | — | — | EP | disclosed |
| EP-3765447-A1 | TRIAZACYCLODODECANSULFONAMIDE (\"TCD\")-BASED PROTEIN SECRETION INHIBITORS | Kezar Life Sciences (US) | 2021-01-20 | — | — | EP | disclosed |
| WO-2019178510-A1 | TRIAZACYCLODODECANSULFONAMIDE (\"TCD\")-BASED PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-09-19 | — | — | WO | disclosed |
| CN-110078725-A | Target compound and its application of ubiquitination degradation GSK-3 β albumen | 中国药科大学 | 2019-08-02 | — | — | CN | disclosed |
| CN-109265400-A | Arginine methyltransferase inhibitor and application thereof | EPIZYME股份有限公司 | 2019-01-25 | — | — | CN | disclosed |
| CN-105339351-B | Arginine methyltransferase inhibitors and uses thereof | EPIZYME股份有限公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-105339351-A | Arginine methyltransferase inhibitors and uses thereof | EPIZYME INC | 2016-02-17 | — | — | CN | disclosed |
| US-20140037573-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | CERULEAN PHARMA INC (US) | 2014-02-06 | — | — | US | disclosed |
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |