Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2939323 | 0.93 | IGF1R (0.57) | IGF1R | |
| SCHEMBL2943342 | 0.91 | IGF1R (0.57) | IGF1R | |
| SCHEMBL2939598 | 0.90 | IGF1R (0.55) | IGF1R | |
| SCHEMBL2935622 | 0.89 | IGF1R (0.56) | IGF1R | |
| SCHEMBL2940717 | 0.86 | IGF1R (0.73) | IGF1R | |
| SCHEMBL2935470 | 0.86 | IGF1R (0.62) | IGF1R | |
| SCHEMBL2937702 | 0.84 | IGF1R (0.46) | IGF1R | |
| SCHEMBL2940375 | 0.84 | IGF1R (0.58) | IGF1R | |
| SCHEMBL2939900 | 0.83 | IGF1R (0.59) | IGF1R | |
| SCHEMBL2942844 | 0.83 | IGF1R (0.74) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |