Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174268 | 0.88 | IGF1R (0.39) | IGF1R | |
| SCHEMBL6174376 | 0.88 | IGF1R (0.39) | IGF1RAR | |
| SCHEMBL6177887 | 0.86 | PIK3CG (0.37) | AR | |
| SCHEMBL6173870 | 0.85 | IGF1R (0.43) | IGF1RAR | |
| SCHEMBL6171343 | 0.85 | IGF1R (0.36) | IGF1R | |
| SCHEMBL6174700 | 0.79 | IGF1R (0.39) | IGF1RAR | |
| SCHEMBL6174696 | 0.79 | SMN1; SMN2 (0.41) | IGF1RAR | |
| SCHEMBL6174021 | 0.79 | IGF1R (0.36) | IGF1R | |
| SCHEMBL6174017 | 0.79 | IGF1R (0.43) | IGF1RAR | |
| SCHEMBL6173683 | 0.78 | IGF1R (0.52) | IGF1RAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |