SCHEMBL6175579

SCHEMBL6175579

B.c1ccc(Nc2ccccn2)nc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.73
MEN1 O00255 2/20 0.73
MAPK10 P53779 1/20 0.73
GFER P55789 1/20 0.73
NPC1 O15118 4/20 0.54
RAB9A P51151 4/20 0.54
PKM P14618 1/20 0.54
ADRA2A P08913 2/20 0.53
ADRA2B P18089 2/20 0.53
ADRA2C P18825 2/20 0.53
CXCR4 P61073 1/20 0.52
KDR P35968 5/20 0.52
ALOX15 P16050 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
KDM4E B2RXH2 1/20 0.52
LMNA P02545 1/20 0.52
TP53 P04637 1/20 0.52
TSHR P16473 1/20 0.52
ALOX12 P18054 1/20 0.52
HTT P42858 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29391624 0.97 KMT2A (0.76) KMT2AMEN1MAPK10GFERNPC1
SCHEMBL221242 0.97 KMT2A (0.76) KMT2AMEN1MAPK10GFERNPC1
Bromide SCHEMBL28368455 0.94 KMT2A (0.73) KMT2AMEN1MAPK10GFERNPC1
SCHEMBL30947359 0.94 KMT2A (0.73) KMT2AMEN1MAPK10GFERNPC1
SCHEMBL10869217 0.94 KMT2A (0.73) KMT2AMEN1MAPK10GFERNPC1
SCHEMBL6175584 0.94 KMT2A (0.73) KMT2AMEN1MAPK10GFERNPC1
SCHEMBL11133606 0.94 KMT2A (0.73) KMT2AMEN1MAPK10GFERNPC1
SCHEMBL6574416 0.94 KMT2A (0.73) KMT2AMEN1MAPK10GFERNPC1
SCHEMBL4243882 0.94 KMT2A (0.73) KMT2AMEN1MAPK10GFERNPC1
SCHEMBL3038944 0.94 KMT2A (0.73) KMT2AMEN1MAPK10GFERNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1340798-B1 Organic element for electroluminescent devices EASTMAN KODAK CO (US) 2005-04-13 EP disclosed
US-6661023-B2 Organic element for electroluminescent devices EASTMAN KODAK COMPANY 2003-12-09 US disclosed
US-20030201415-A1 Organic element for electroluminescent devices EASTMAN KODAK COMPANY 2003-10-30 US disclosed
EP-1340798-A2 Organic element for electroluminescent devices EASTMAN KODAK COMPANY (US) 2003-09-03 EP disclosed