Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 17/20 | 0.67 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3874198 | 0.86 | TRPV1 (0.73) | TRPV1TRPV4 | |
| SCHEMBL3873320 | 0.85 | TRPV1 (0.78) | TRPV1TRPV4 | |
| SCHEMBL3872091 | 0.83 | TRPV1 (0.78) | TRPV1TRPV4 | |
| SCHEMBL14083879 | 0.83 | TRPV1 (0.78) | TRPV1TRPV4 | |
| SCHEMBL14083896 | 0.83 | TRPV1 (0.67) | TRPV1TRPV4 | |
| SCHEMBL4590986 | 0.83 | TRPV1 (0.67) | TRPV1TRPV4 | |
| SCHEMBL14082841 | 0.82 | TRPV1 (0.77) | TRPV1TRPV4 | |
| SCHEMBL14083467 | 0.81 | TRPV1 (0.75) | TRPV1TRPV4 | |
| SCHEMBL3872137 | 0.81 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL3881001 | 0.81 | TRPV1 (1.00) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575918-A2 | SUBSTITUTED BIARYL-4-CARBOXYLIC ACID ARYLAMIDE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2005-09-21 | — | — | EP | claimed |
| WO-2004056774-A2 | SUBSTITUTED BIPHENYL-4-CARBOXYLIC ACID ARYLAMIDE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2004-07-08 | — | — | WO | claimed |