Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 19/20 | 0.75 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.65 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.65 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.65 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5627243 | 0.95 | PTGER1 (0.84) | PTGER1TBXA2RPTGER4PTGER3 | |
| SCHEMBL5629762 | 0.91 | PTGER1 (0.90) | PTGER1TBXA2RPTGER4PTGER3 | |
| SCHEMBL14527469 | 0.88 | PTGER1 (0.82) | PTGER1TBXA2RPTGER4PTGER3 | |
| SCHEMBL5627645 | 0.87 | PTGER1 (0.86) | PTGER1TBXA2RPTGER4PTGER3 | |
| SCHEMBL6239084 | 0.86 | PTGER1 (0.87) | PTGER1TBXA2RPTGER4PTGER3 | |
| SCHEMBL14527462 | 0.86 | PTGER1 (1.00) | PTGER1TBXA2RPTGER4PTGER3 | |
| SCHEMBL5630032 | 0.86 | PTGER1 (0.86) | PTGER1TBXA2RPTGER4PTGER3 | |
| SCHEMBL5628930 | 0.86 | PTGER1 (0.83) | PTGER1TBXA2RPTGER4PTGER3 | |
| SCHEMBL5629470 | 0.84 | PTGER1 (1.00) | PTGER1TBXA2RPTGER4PTGER3 | |
| SCHEMBL5627866 | 0.84 | PTGER1 (0.71) | PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509499-A1 | PYRROLE COMPOUNDS FOR THE TREATMENT OF PROSTAGLANDIN MEDIATED DISEASES | GLAXO GROUP LIMITED (GB) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003101959-A1 | PYRROLE COMPOUNDS FOR THE TREATMENT OF PROSTAGLANDIN MEDIATED DISEASES | GLAXO GROUP LIMITED (GB) | 2003-12-11 | — | — | WO | disclosed |