Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 19/20 | 0.76 |
| ▸ | CNR2 | P34972 | 6/20 | 0.76 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6190763 | 0.87 | CNR1 (0.85) | CNR1CNR2 | |
| SCHEMBL5041587 | 0.87 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL675014 | 0.87 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL673526 | 0.87 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL5038475 | 0.86 | CNR1 (0.98) | CNR1CNR2 | |
| SCHEMBL6176217 | 0.85 | CNR1 (0.55) | CNR1CNR2CDC7DBF4 | |
| SCHEMBL4477519 | 0.84 | CNR1 (0.57) | CNR1CNR2CDC7DBF4 | |
| SCHEMBL5034238 | 0.84 | CDC7 (0.60) | CNR1CNR2CDC7DBF4 | |
| SCHEMBL5043843 | 0.82 | CNR1 (0.89) | CNR1CNR2 | |
| SCHEMBL5036931 | 0.82 | CNR1 (0.89) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592403-A1 | AQUEOUS DISPERSION COMPRISING STABLE NANOPARTICLES OF A WATER-INSOLUBLE THIAZOLE DERIVATIVE AND EXCIPIENTS LIKE MIDDLE CHAIN TRIGLYCERIDES | AstraZeneca AB (SE) | 2005-11-09 | — | — | EP | disclosed |
| EP-1581214-A1 | 4,5-DIARYLTHIAZOLE DERIVATIVES AS CB-1 LIGANDS | Astrazeneca AB (SE) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004069226-A1 | AQUEOUS DISPERSION COMPRISING STABLE NANOPARTICLES OF A WATER-INSOLUBLE THIAZOLE DERIVATIVE AND EXCIPIENTS LIKE MIDDLE CHAIN TRIGLYCERIDES | ASTRAZENECA AB (SE) | 2004-08-19 | — | — | WO | disclosed |
| WO-2004058255-A1 | 4, 5-DIARYLTHIAZOLE DERIVATIVES AS CB-1 LIGANDS | ASTRAZENECA AB (SE) | 2004-07-15 | — | — | WO | disclosed |