SCHEMBL6176530

SCHEMBL6176530

CC(C)(C)O[CH]OC(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.50
ALDH1A1 P00352 2/20 0.43
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6178900 0.81
SCHEMBL6181157 0.73 TDP1 (0.36) TDP1ALDH1A1
SCHEMBL6175844 0.73
SCHEMBL8726056 0.73 TDP1 (0.50) TDP1ALDH1A1TSHR
SCHEMBL8726055 0.73 TDP1 (0.50) TDP1ALDH1A1TSHR
SCHEMBL12744846 0.73 TDP1 (0.50) TDP1ALDH1A1TSHR
SCHEMBL125065 0.70
SCHEMBL6179776 0.69 TDP1 (0.33) TDP1
SCHEMBL2068703 0.67
SCHEMBL49310 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118355020-A Therapeutic compounds for HIV virus infection 吉利德科学公司 2024-07-16 CN disclosed
EP-0945445-B9 1,5-BENZODIAZEPINE DERIVATIVES ZERIA PHARM CO LTD (JP) 2005-12-28 EP disclosed
EP-0945445-B1 1,5-BENZODIAZEPINE DERIVATIVES ZERIA PHARM CO LTD (JP) 2003-09-03 EP disclosed
US-6239131-B1 WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. ZERIA PHARMACEUTICAL CO., LTD. (JP) 2001-05-29 US disclosed
EP-0945445-A1 1,5-BENZODIAZEPINE DERIVATIVES ZERIA PHARMACEUTICAL CO., LTD. (JP) 1999-09-29 EP disclosed
US-5807806-A Benzoylpyrazole derivatives having specific substituents and herbicide NIPPON SODA CO., LTD. (JP) 1998-09-15 US disclosed
US-4354972-A Synthesis of steroids KAISER EMIL T 1982-10-19 US disclosed