Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 13/20 | 0.59 |
| ▸ | KCNQ2 | O43526 | 13/20 | 0.59 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.56 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.56 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178002 | 0.85 | KCNQ3 (0.58) | KCNQ3KCNQ2KCNE1KCNQ1MEN1 | |
| SCHEMBL6179704 | 0.80 | KCNQ3 (0.58) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL5687094 | 0.76 | CXCR1 (0.56) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL6178319 | 0.75 | KCNQ3 (0.53) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL5213301 | 0.75 | KCNQ3 (1.00) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL14339872 | 0.74 | KCNQ3 (1.00) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL4061450 | 0.74 | P4HTM (0.56) | RAB9A | |
| SCHEMBL31305934 | 0.74 | MCHR1 (0.56) | KCNQ3KCNQ2KCNE1KCNQ1MEN1 | |
| SCHEMBL1290685 | 0.74 | MCHR1 (0.56) | KCNQ3KCNQ2KCNE1KCNQ1MEN1 | |
| SCHEMBL6179011 | 0.74 | KCNQ3 (0.55) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066261-B1 | PYRIDINE DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME | OTSUKA PHARMA CO LTD (JP) | 2005-11-23 | — | — | EP | disclosed |
| US-6511995-B1 | Inhibits collagen synthesis, which is useful for prophylaxis or treatment of fibrosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-28 | — | — | US | disclosed |