SCHEMBL6177789

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7491106	1.00	MAPK14 (0.59)	MAPK14MAPK11MAPK13MAPK12GCGR
	SCHEMBL5255543	0.84	MAPK11 (0.52)	MAPK14MAPK11MAPK13MAPK12GCGR
	SCHEMBL19972125	0.83	MKNK1 (0.51)	MAPK14MAPK11MAPK13MAPK12SRC
	SCHEMBL14519385	0.83	MKNK1 (0.51)	MAPK14MAPK11MAPK13MAPK12SRC
	SCHEMBL5258469	0.82	MAPK14 (0.69)	MAPK14MAPK11MAPK13MAPK12GCGR
	SCHEMBL14519418	0.82	MAPK14 (0.69)	MAPK14MAPK11MAPK13MAPK12GCGR
	SCHEMBL8836383	0.82	MAPK14 (0.47)	MAPK14MAPK11MAPK13MAPK12
	SCHEMBL8836207	0.82	MAPK14 (0.59)	MAPK14MAPK11MAPK13MAPK12GCGR
	SCHEMBL8836352	0.82	KDM4E (0.50)	MAPK14MAPK11
	SCHEMBL14521828	0.82	MAPK14 (0.69)	MAPK14MAPK11MAPK13MAPK12GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.