SCHEMBL6178032

SCHEMBL6178032

C1=C\[N]CCCCC/1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7216416 1.00
SCHEMBL7498312 1.00
SCHEMBL34926 0.97
SCHEMBL9143 0.88
SCHEMBL3315 0.74
SCHEMBL11294683 0.72
SCHEMBL1162932 0.69
SCHEMBL4362788 0.65 HDAC3 (0.31)
SCHEMBL3628921 0.65 HDAC3 (0.31)
SCHEMBL3629251 0.65 HDAC3 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024141011-A1 COMPLEMENT FACTOR B INHIBITOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF 深圳晶泰科技有限公司 2024-07-04 WO claimed
WO-2024141011-A1 COMPLEMENT FACTOR B INHIBITOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF 深圳晶泰科技有限公司 2024-07-04 WO disclosed
CN-118221643-A Oxime-containing compound with STING inhibition effect, and pharmaceutical composition and application thereof 杭州中美华东制药有限公司 2024-06-21 CN disclosed
WO-2024032597-A1 AMIDE COMPOUND HAVING STING INHIBITORY EFFECT, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 杭州中美华东制药有限公司 2024-02-15 WO disclosed
CN-113766914-B Pentaneamidine analogues and uses thereof 美商奥润沙公司 2024-02-13 CN disclosed
CN-114430755-A Small molecule membranes for sacrificial support, surface protection and latency management 朗姆研究公司 2022-05-03 CN disclosed
CN-113766914-A Pentamidine analogs and uses thereof 美商奥润沙公司 2021-12-07 CN disclosed
EP-1201660-B1 Glucocorticoid receptor modulators PFIZER PROD INC (US) 2005-08-31 EP disclosed
US-6852719-B2 Dietetics; antidiabetic agents; antiinflammatory agents PFIZER INC. (US) 2005-02-08 US disclosed
US-20040014741-A1 Glucocorticoid receptor modulators LIU KEVIN K (US) 2004-01-22 US disclosed
EP-0632052-B1 Endothelin antagonistic peptides BANYU PHARMA CO LTD (JP) 1998-09-30 EP disclosed
US-5691315-A CARDIOVASCULAR DISORDERS; VASODILATOR; BRONCHODILATOR BANYU PHARMACEUTICAL CO., LTD. (JP) 1997-11-25 US disclosed
US-5614498-A OLIGOPEPTIDES, BRONCHDILATORS BANYU PHARMACEUTICAL CO., LTD. (JP) 1997-03-25 US disclosed
US-5496928-A Endothelin antagonistic substance BANYU PHARMACEUTICAL CO., LTD. (JP) 1996-03-05 US disclosed
US-5494897-A PENTAPEPTIDES, LINEAR OR CYCLIC BANYU PHARMACEUTICAL CO., LTD. (JP) 1996-02-27 US disclosed
US-5470833-A Vasodilators, bronchodilators BANYU PHARMACEUTICAL CO., LTD. (JP) 1995-11-28 US disclosed
US-5444152-A Vasolidator or bronchodilator BANYU PHARMACEUTICAL CO., LTD. (JP) 1995-08-22 US disclosed
EP-0632052-A1 Endothelin antagonistic peptides BANYU PHARMACEUTICAL CO., LTD. (JP) 1995-01-04 EP disclosed
EP-0555537-A2 Endothelin antagonistic substance BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-08-18 EP disclosed
EP-0460679-A2 Endothelin antagonistic peptide derivatives Banyu Pharmaceutical Co., Ltd. (JP) 1991-12-11 EP disclosed