Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 19/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861305 | 0.94 | SERPINE1 (0.51) | SERPINE1 | |
| SCHEMBL6177196 | 0.86 | SERPINE1 (0.55) | SERPINE1 | |
| SCHEMBL7866163 | 0.84 | SERPINE1 (0.54) | SERPINE1 | |
| SCHEMBL7391101 | 0.80 | CA12 (0.44) | MCL1 | |
| SCHEMBL6178817 | 0.80 | CA12 (0.41) | MCL1 | |
| Ammonia Solution, Strong SCHEMBL8176215 | 0.80 | CA12 (0.43) | MCL1 | |
| Ammonia Solution, Strong SCHEMBL8176216 | 0.80 | CA12 (0.43) | MCL1 | |
| SCHEMBL7866186 | 0.79 | SERPINE1 (0.51) | SERPINE1 | |
| SCHEMBL6177057 | 0.75 | SERPINE1 (0.56) | SERPINE1 | |
| SCHEMBL7869562 | 0.75 | SERPINE1 (0.56) | SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092716-B1 | Derivatives of benzothiophenes, benzofurans and indoles, method for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-02-16 | — | — | EP | disclosed |
| US-6302837-B1 | ANTICOAGULANTS | ADIR ET COMPAGNIE (FR) | 2001-10-16 | — | — | US | disclosed |
| EP-1092716-A2 | Derivatives of benzothiophenes, benzofurans and indoles, method for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-04-18 | — | — | EP | disclosed |