Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5868105 | 0.96 | F10 (0.38) | F10ACHE | |
| SCHEMBL5868094 | 0.91 | F10 (0.42) | F10ACHE | |
| SCHEMBL5868300 | 0.85 | F10 (0.41) | F10ACHEKDM4EALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL5868142 | 0.82 | F10 (0.40) | F10ACHEHPGD | |
| Trifluoroacetic Acid SCHEMBL5867994 | 0.82 | KDM4E (0.40) | F10ACHEKDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5868135 | 0.80 | F10 (0.43) | F10ACHEHPGD | |
| SCHEMBL5868138 | 0.77 | F10 (0.43) | F10 | |
| Trifluoroacetic Acid SCHEMBL5868319 | 0.77 | F10 (0.53) | F10ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL5868199 | 0.76 | F10 (0.40) | F10 | |
| SCHEMBL5867984 | 0.75 | F10 (0.47) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289954-B1 | SERINE PROTEASE INHIBITORS | LILLY CO ELI (US) | 2005-09-14 | — | — | EP | disclosed |