Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 4/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180789 | 1.00 | SCN4A (0.40) | SCN4AKDRMAPK1KDM4EF2 | |
| Hydrochloric Acid SCHEMBL6092090 | 0.99 | SCN4A (0.40) | SCN4AKDRMAPK1KDM4EF2 | |
| Hydrochloric Acid SCHEMBL6094251 | 0.99 | SCN4A (0.40) | SCN4AKDRMAPK1KDM4EF2 | |
| SCHEMBL6094313 | 0.90 | SCN4A (0.39) | SCN4AKDRMAPK1KDM4EF2 | |
| SCHEMBL6093494 | 0.90 | SCN4A (0.39) | SCN4AKDRMAPK1KDM4EF2 | |
| SCHEMBL6184253 | 0.86 | SCN4A (0.41) | SCN4AKDRMAPK1KDM4EF2 | |
| SCHEMBL6179226 | 0.86 | DPP4 (0.46) | — | |
| Hydrochloric Acid SCHEMBL6094528 | 0.85 | F2 (0.46) | KDRF2PDGFRB | |
| Hydrochloric Acid SCHEMBL6095357 | 0.85 | DPP4 (0.46) | — | |
| Hydrochloric Acid SCHEMBL7129856 | 0.85 | DPP4 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1287018-B1 | THROMBIN INHIBITORS | LEK TOVARNA FARMACEVTSKIH (SI) | 2005-01-19 | — | — | EP | claimed |