Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29158025 | 0.90 | SMN1; SMN2 (0.76) | MAPTMAPK1SMN1; SMN2TSHRPOLB | |
| SCHEMBL11196639 | 0.86 | SMN1; SMN2 (0.81) | MAPTMAPK1SMN1; SMN2TSHRPOLB | |
| SCHEMBL4651272 | 0.85 | MAPT (1.00) | MAPTMAPK1SMN1; SMN2TSHRPOLB | |
| SCHEMBL29989633 | 0.85 | MAPT (1.00) | MAPTMAPK1SMN1; SMN2TSHRPOLB | |
| SCHEMBL6173619 | 0.84 | MAPK1 (0.72) | MAPTMAPK1SMN1; SMN2TSHRPOLB | |
| SCHEMBL25263135 | 0.82 | MAPK1 (0.69) | MAPTMAPK1SMN1; SMN2TSHRPOLB | |
| SCHEMBL25306797 | 0.81 | MAPK1 (0.68) | MAPTMAPK1SMN1; SMN2TSHRPOLB | |
| SCHEMBL30908553 | 0.81 | GAA (0.64) | MAPTKMT2AGAANPC1RAB9A | |
| SCHEMBL14062228 | 0.80 | GAA (0.76) | MAPTSMN1; SMN2TSHRPOLBGAA | |
| SCHEMBL29393380 | 0.80 | GAA (0.76) | MAPTSMN1; SMN2TSHRPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575918-A2 | SUBSTITUTED BIARYL-4-CARBOXYLIC ACID ARYLAMIDE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2005-09-21 | — | — | EP | claimed |
| WO-2004056774-A2 | SUBSTITUTED BIPHENYL-4-CARBOXYLIC ACID ARYLAMIDE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2004-07-08 | — | — | WO | claimed |