Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.73 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178962 | 0.90 | MAPK14 (0.89) | MAPK14WNT3APRKACAROCK1KMT2A | |
| SCHEMBL6176420 | 0.89 | MAPK14 (0.81) | MAPK14WNT3APRKACAROCK1GSK3B | |
| SCHEMBL6180514 | 0.88 | MAPK14 (0.89) | MAPK14WNT3APRKACAROCK1MEN1 | |
| SCHEMBL6177762 | 0.87 | MAPK14 (0.78) | MAPK14WNT3APRKACAROCK1GSK3B | |
| SCHEMBL6178004 | 0.86 | MAPK14 (0.82) | MAPK14WNT3APRKACAROCK1GSK3B | |
| SCHEMBL6179153 | 0.85 | MAPK14 (0.81) | MAPK14WNT3APRKACAROCK1KMT2A | |
| SCHEMBL6179313 | 0.85 | MAPK14 (0.81) | MAPK14WNT3APRKACAROCK1KMT2A | |
| SCHEMBL6177800 | 0.85 | MAPK14 (1.00) | MAPK14WNT3APRKACAROCK1GSK3B | |
| SCHEMBL6176676 | 0.84 | MAPK14 (0.76) | MAPK14PRKACAROCK1MEN1KMT2A | |
| SCHEMBL6177353 | 0.84 | MAPK14 (0.79) | MAPK14WNT3APRKACAROCK1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142890-B1 | AMINOPYRAZOLE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2005-08-03 | — | — | EP | disclosed |
| US-6511997-B1 | For treatment of a disease associated with tumor necrosis factor alpha, interleukin 1, interleukin 6 or cyclooxygenase II; such as irritable bowel disease | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2003-01-28 | — | — | US | disclosed |
| EP-1142890-A1 | AMINOPYRAZOLE DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |