Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27657207 | 0.87 | HTT (0.52) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL6179781 | 0.84 | HSD17B10 (0.33) | — | |
| SCHEMBL3203801 | 0.80 | TSHR (0.48) | TSHRCYP3A4ADRB2ADRB1ADRB3 | |
| SCHEMBL19259385 | 0.80 | TSHR (0.48) | TSHRCYP3A4ADRB2ADRB1ADRB3 | |
| SCHEMBL4838438 | 0.80 | TSHR (0.48) | TSHRCYP3A4ADRB2ADRB1ADRB3 | |
| SCHEMBL10516 | 0.78 | — | — | |
| SCHEMBL8888918 | 0.78 | — | — | |
| SCHEMBL20414615 | 0.78 | HRH3 (0.36) | — | |
| SCHEMBL8888925 | 0.78 | CYP4F2 (0.38) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL302981 | 0.78 | TSHR (0.55) | TSHRCYP3A4ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104977367-A | Method for detecting 20 kinds of beta-stimulant drug residues in livestock urine | COFCO NUTRITION & HEALTH RES INST CO LTD | 2015-10-14 | — | — | CN | claimed |
| CN-104977367-A | Method for detecting 20 kinds of beta-stimulant drug residues in livestock urine | COFCO NUTRITION & HEALTH RES INST CO LTD | 2015-10-14 | — | — | CN | disclosed |
| EP-0945445-B9 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-0945445-B1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |