Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4528725 | 0.98 | ACACB (0.44) | ACACBACACAPTPN1PSMD14PLA2G1B | |
| SCHEMBL6198957 | 0.90 | ACACB (0.40) | ACACBACACAPTPN1 | |
| SCHEMBL16074757 | 0.81 | CYP4F2 (0.41) | FFAR1LMNAALDH1A1HSD17B10 | |
| SCHEMBL21986972 | 0.81 | CYP4F2 (0.41) | FFAR1LMNAALDH1A1HSD17B10 | |
| SCHEMBL22558017 | 0.81 | CYP4F2 (0.41) | FFAR1LMNAALDH1A1HSD17B10 | |
| SCHEMBL28374111 | 0.81 | CYP4F2 (0.41) | FFAR1LMNAALDH1A1HSD17B10 | |
| SCHEMBL28368582 | 0.81 | CYP4F2 (0.41) | FFAR1LMNAALDH1A1HSD17B10 | |
| SCHEMBL27886724 | 0.81 | SMN1; SMN2 (0.38) | LMNAALDH1A1HSD17B10 | |
| SCHEMBL16074952 | 0.80 | ACACB (0.46) | ACACBACACAPTPN1PSMD14PLA2G1B | |
| SCHEMBL16074886 | 0.80 | ACACB (0.46) | ACACBACACAPTPN1PSMD14PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597223-A2 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | Esperion Therapeutics Inc. (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004067489-A2 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2004-08-12 | — | — | WO | disclosed |