SCHEMBL6180408

SCHEMBL6180408

CCCCCS(=O)(=O)NC(=O)CCc1cnc(C)n1Cc1ccc(Cl)cc1Cl

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6181012 0.81 PPARG (0.68) PPARG
SCHEMBL6181016 0.81 PPARG (0.68) PPARG
SCHEMBL3208039 0.80 PPARG (1.00) PPARG
SCHEMBL3206879 0.80 PPARG (1.00) PPARG
SCHEMBL3213650 0.78 PPARG (1.00) PPARG
SCHEMBL3205612 0.77 PPARG (1.00) PPARG
SCHEMBL3215965 0.77 PPARG (1.00) PPARG
SCHEMBL3219247 0.77 PPARG (0.77) PPARG
SCHEMBL3217092 0.77 PPARG (1.00) PPARG
SCHEMBL3204703 0.76 PPARG (1.00) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1000932-B9 AROMATIC RING DERIVATIVES FUJISAWA PHARMACEUTICAL CO (JP) 2005-12-28 EP disclosed
EP-1000932-B1 AROMATIC RING DERIVATIVES FUJISAWA PHARMACEUTICAL CO (JP) 2004-09-15 EP disclosed
US-6242474-B1 SULFONYLCARBAMOYLALKYLIMIDAZOLE DERIVATIVES; ANTIDIABETIC AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-06-05 US disclosed
EP-1000932-A1 AROMATIC RING DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-05-17 EP disclosed