Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 17/20 | 0.51 |
| ▸ | GRPR | P30550 | 13/20 | 0.51 |
| ▸ | FPR1 | P21462 | 2/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184335 | 0.88 | NMBR (0.64) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6181252 | 0.87 | NMBR (0.64) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6179976 | 0.86 | NMBR (0.65) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6250091 | 0.84 | NMBR (0.47) | NMBRGRPRTACR1 | |
| SCHEMBL6252799 | 0.83 | NMBR (0.49) | NMBRGRPRTACR1 | |
| SCHEMBL6185509 | 0.83 | NMBR (0.72) | NMBRGRPR | |
| SCHEMBL6251392 | 0.82 | TACR1 (0.48) | NMBRGRPRTACR1 | |
| SCHEMBL6250533 | 0.82 | NMBR (0.50) | NMBRGRPRTACR1 | |
| SCHEMBL6252282 | 0.82 | NMBR (0.48) | NMBRGRPRTACR1 | |
| SCHEMBL6251949 | 0.81 | TACR1 (0.52) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920424-B1 | NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 2005-11-30 | — | — | EP | claimed |
| US-6194437-B1 | ANTIDEPRESSANTS; ANTICANCER AGENTS; GASTROINTESTINAL DISORDERS; COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY | 2001-02-27 | — | — | US | claimed |