Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 15/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5628945 | 0.91 | PTGER1 (0.52) | PTGER1MAOBMTNR1BCCR5 | |
| SCHEMBL6191223 | 0.87 | AKR1B1 (0.53) | PTGER1MAOBMTNR1BAKR1A1AKR1B1 | |
| SCHEMBL5627116 | 0.86 | MAOB (0.51) | PTGER1MAOBMAPK14 | |
| SCHEMBL6188332 | 0.85 | MAOB (0.53) | PTGER1MAOBCCR5 | |
| SCHEMBL5628010 | 0.84 | MAOB (0.52) | PTGER1MAOBMAPK14 | |
| SCHEMBL5627661 | 0.80 | PTGER1 (0.50) | PTGER1MTNR1BAKR1B1 | |
| SCHEMBL5627697 | 0.80 | PTGER1 (0.52) | PTGER1MAOB | |
| SCHEMBL6169233 | 0.80 | MAOB (0.47) | PTGER1MAOBMAPK14 | |
| SCHEMBL5468595 | 0.78 | MAOB (0.46) | PTGER1MAOB | |
| SCHEMBL6191453 | 0.77 | MAOB (0.51) | PTGER1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509499-A1 | PYRROLE COMPOUNDS FOR THE TREATMENT OF PROSTAGLANDIN MEDIATED DISEASES | GLAXO GROUP LIMITED (GB) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003101959-A1 | PYRROLE COMPOUNDS FOR THE TREATMENT OF PROSTAGLANDIN MEDIATED DISEASES | GLAXO GROUP LIMITED (GB) | 2003-12-11 | — | — | WO | disclosed |