Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181280 | 0.94 | ACACB (0.41) | ACACBACACA | |
| SCHEMBL6179615 | 0.94 | ACACB (0.50) | ACACBACACAFFAR4FFAR1 | |
| SCHEMBL12945239 | 0.92 | ACACB (0.53) | ACACBACACAFFAR4FFAR1 | |
| SCHEMBL12092647 | 0.87 | ACACB (0.44) | ACACBACACAFFAR4FFAR1 | |
| SCHEMBL6199247 | 0.86 | ACACB (0.36) | ACACBACACA | |
| SCHEMBL12092644 | 0.85 | ACACB (0.47) | ACACBACACAFFAR4FFAR1 | |
| SCHEMBL13053918 | 0.81 | ACACB (0.31) | ACACBACACA | |
| SCHEMBL13053866 | 0.77 | ACACB (0.30) | ACACBACACA | |
| SCHEMBL13106118 | 0.77 | ACACB (0.36) | ACACBACACA | |
| SCHEMBL13106127 | 0.75 | ACACB (0.39) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597223-A2 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | Esperion Therapeutics Inc. (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004067489-A2 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2004-08-12 | — | — | WO | disclosed |