Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377310 | 0.87 | F10 (0.61) | F10MAPT | |
| SCHEMBL1377197 | 0.86 | F10 (0.61) | F10 | |
| SCHEMBL1379829 | 0.85 | F10 (0.63) | F10MAPTCYP2C9 | |
| SCHEMBL4027950 | 0.79 | F10 (1.00) | F10 | |
| SCHEMBL4034268 | 0.79 | F10 (1.00) | F10 | |
| SCHEMBL5627563 | 0.78 | F10 (0.60) | F10CYP2C9 | |
| SCHEMBL5629697 | 0.78 | F10 (0.60) | F10CYP2C9 | |
| SCHEMBL5626014 | 0.77 | F10 (0.64) | F10 | |
| SCHEMBL5626649 | 0.77 | F10 (0.64) | F10 | |
| SCHEMBL5627049 | 0.77 | F10 (0.61) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562939-A1 | CARBOXAMIDES | MERCK PATENT GmbH (DE) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004046138-A1 | CARBOXAMIDES | MERCK PATENT GMBH (DE) | 2004-06-03 | — | — | WO | disclosed |