Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.63 |
| ▸ | PREP | P48147 | 2/20 | 0.57 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26688737 | 0.78 | DPP4 (1.00) | DPP4PREPDPP8DPP9 | |
| SCHEMBL8261098 | 0.75 | DPP4 (0.73) | DPP4PREPDPP8DPP9 | |
| SCHEMBL4419337 | 0.74 | DPP4 (0.82) | DPP4DPP8DPP9 | |
| SCHEMBL4419343 | 0.74 | DPP4 (0.82) | DPP4DPP8DPP9 | |
| SCHEMBL4419347 | 0.74 | DPP4 (0.82) | DPP4DPP8DPP9 | |
| SCHEMBL18621797 | 0.74 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL13417345 | 0.74 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL7203181 | 0.73 | DPP4 (0.70) | DPP4PREPDPP8DPP9 | |
| SCHEMBL7203170 | 0.73 | DPP4 (0.70) | DPP4PREPDPP8DPP9 | |
| SCHEMBL16272853 | 0.72 | DPP4 (0.69) | DPP4PREPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492777-A1 | THIAZOLIDINE-4-CARBONITRILES AND ANALOGUES AND THEIR USE AS DIPEPTIDYL-PEPTIDASE INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2005-01-05 | — | — | EP | claimed |
| WO-2003084940-A1 | THIAZOLIDINE-4-CARBONITRILES AND ANALOGUES AND THEIR USE AS DIPEPTIDYL-PEPTIDAS INHIBITORS | SANKARANARAYANAN ALANGUDI (IN) | 2003-10-16 | — | — | WO | claimed |