Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19160082 | 0.85 | CYP2C19 (0.60) | CYP2C19HIF1AFFAR1CPT2TDP1 | |
| SCHEMBL2737150 | 0.85 | CYP2C19 (0.60) | CYP2C19HIF1AFFAR1CPT2TDP1 | |
| SCHEMBL12094505 | 0.84 | CYP2C19 (0.62) | CYP2C19HIF1AFFAR1CPT2TDP1 | |
| SCHEMBL12094514 | 0.83 | CYP2C19 (0.66) | CYP2C19HIF1AFFAR1CPT2TDP1 | |
| SCHEMBL3280386 | 0.82 | CYP2C19 (0.64) | CYP2C19HIF1AFFAR1CPT2TDP1 | |
| SCHEMBL7021873 | 0.81 | CYP2C19 (0.39) | CYP2C19HIF1ARIPK1CYP1A2CYP2D6 | |
| SCHEMBL7027201 | 0.81 | CYP2C19 (0.39) | CYP2C19HIF1ARIPK1CYP1A2CYP2D6 | |
| SCHEMBL7027006 | 0.81 | CYP2C19 (0.39) | CYP2C19HIF1ARIPK1CYP1A2CYP2D6 | |
| SCHEMBL7027001 | 0.81 | CYP2C19 (0.40) | CYP2C19HIF1AMAPTKMT2AKIF11 | |
| SCHEMBL3286672 | 0.80 | CYP2C19 (0.66) | CYP2C19HIF1AFFAR1CPT2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597223-A2 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | Esperion Therapeutics Inc. (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004067489-A2 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2004-08-12 | — | — | WO | disclosed |