Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 13/20 | 0.40 |
| ▸ | HTR2A | P28223 | 9/20 | 0.40 |
| ▸ | HTR2B | P41595 | 8/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LATS1 | O95835 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL906101 | 0.90 | HTR2C (0.40) | HTR2CHTR2AHTR2BKCNH2HTR1A | |
| SCHEMBL237951 | 0.89 | HTR2C (0.42) | HTR2CHTR2AHTR2BKCNH2HTR1A | |
| SCHEMBL2639684 | 0.89 | HTR2C (0.42) | HTR2CHTR2AHTR2BKCNH2HTR1A | |
| SCHEMBL905805 | 0.89 | HTR2C (0.42) | HTR2CHTR2AHTR2BKCNH2LATS1 | |
| SCHEMBL4313537 | 0.88 | HTR2C (0.42) | HTR2CHTR2AHTR2BKCNH2HTR1A | |
| SCHEMBL2639295 | 0.88 | HTR2C (0.42) | HTR2CHTR2AHTR2BKCNH2HTR1A | |
| SCHEMBL906015 | 0.86 | HTR2C (0.40) | HTR2CHTR2AHTR2BKCNH2HTR1A | |
| SCHEMBL6047120 | 0.86 | HTR2C (0.42) | HTR2CHTR2AHTR2BKCNH2HTR1A | |
| SCHEMBL237834 | 0.86 | HTR2C (0.42) | HTR2CHTR2AHTR2BKCNH2HTR1A | |
| SCHEMBL905949 | 0.86 | HTR2C (0.43) | HTR2CHTR2AHTR2BKCNH2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513831-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Biovitrum AB (SE) | 2005-03-16 | — | — | EP | claimed |
| WO-2004000830-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | BIOVITRUM AB (SE) | 2003-12-31 | — | — | WO | claimed |
| EP-1513831-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Biovitrum AB (SE) | 2005-03-16 | — | — | EP | disclosed |
| WO-2004000830-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | BIOVITRUM AB (SE) | 2003-12-31 | — | — | WO | disclosed |