Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.72 |
| ▸ | PPARA | Q07869 | 15/20 | 0.72 |
| ▸ | PPARG | P37231 | 9/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5514485 | 0.94 | PPARD (0.82) | PPARDPPARAPPARG | |
| SCHEMBL5513436 | 0.94 | PPARD (0.76) | PPARDPPARAPPARG | |
| SCHEMBL5519944 | 0.89 | PPARD (0.68) | PPARDPPARAPPARG | |
| SCHEMBL5517567 | 0.87 | PPARD (0.65) | PPARDPPARAPPARG | |
| SCHEMBL5513213 | 0.84 | PPARD (1.00) | PPARDPPARAPPARG | |
| SCHEMBL5510088 | 0.83 | PPARD (0.83) | PPARDPPARAPPARG | |
| SCHEMBL5513448 | 0.83 | PPARD (0.64) | PPARDPPARAPPARG | |
| SCHEMBL5509985 | 0.81 | PPARD (0.68) | PPARDPPARAPPARG | |
| SCHEMBL5506830 | 0.81 | PPARD (1.00) | PPARDPPARAPPARG | |
| SCHEMBL5515984 | 0.79 | PPARD (0.70) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494989-A2 | COMPOUNDS THAT MODULATE PPAR ACTIVITY AND METHODS FOR THEIR PREPARATION | WARNER-LAMBERT COMPANY LLC (US) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003084916-A2 | COMPOUNDS THAT MODULATE PPAR ACTIVITY AND METHODS FOR THEIR PREPARATION | WARNER-LAMBERT COMPANY LLC (US) | 2003-10-16 | — | — | WO | disclosed |