SCHEMBL6182544

SCHEMBL6182544

Cc1ccc(S(=O)(=O)Nc2cc(C)c([C@@H]3CN[C@H](C(=O)N4CCC[C@H]4C#N)C3)c(C)c2)cc1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6185919 0.86 DPP4 (0.81) DPP4
SCHEMBL6184679 0.86 DPP4 (0.68) DPP4
SCHEMBL6185922 0.85 DPP4 (0.67) DPP4
SCHEMBL6183213 0.85 DPP4 (0.64) DPP4
SCHEMBL6183333 0.84 DPP4 (0.66) DPP4
SCHEMBL6183215 0.84 DPP4 (0.66) DPP4
SCHEMBL6182542 0.84 DPP4 (0.66) DPP4
SCHEMBL6184325 0.84 DPP4 (0.66) DPP4
SCHEMBL6187591 0.84 DPP4 (0.66) DPP4
SCHEMBL6183026 0.84 DPP4 (0.66) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1535906-A1 NITROGEN-CONTAINING COMPOUNDS ONO PHARMACEUTICAL CO., LTD. (JP) 2005-06-01 EP disclosed