Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 10/20 | 0.46 |
| ▸ | PPARA | Q07869 | 9/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304130 | 0.85 | CYP19A1 (0.43) | CYP1A2PPARGPPARASRRALPI | |
| SCHEMBL28553377 | 0.83 | MDM2 (0.53) | CYP1A2PPARGPPARAATML3MBTL1 | |
| SCHEMBL11222109 | 0.81 | CYP1A2 (0.47) | CYP1A2PPARGPPARASRRALPI | |
| SCHEMBL5198959 | 0.81 | ATM (0.47) | CYP1A2ADRB2ADRB1ADRB3ATM | |
| SCHEMBL6310921 | 0.80 | NAMPT (0.52) | PPARGPPARA | |
| SCHEMBL4197351 | 0.80 | HSD17B10 (0.50) | CYP1A2PPARGPPARAATML3MBTL1 | |
| SCHEMBL1449126 | 0.80 | ALPI (0.61) | CYP1A2PPARGPPARASRRALPI | |
| SCHEMBL7780318 | 0.80 | ALPI (0.61) | CYP1A2PPARGPPARASRRALPI | |
| SCHEMBL27373982 | 0.80 | ALPI (0.61) | CYP1A2PPARGPPARASRRALPI | |
| SCHEMBL27641992 | 0.80 | CYP1A2 (0.46) | CYP1A2PPARGPPARAATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583741-A1 | 1-SUBSTITUTED-3-PYRROLIDINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories, Limited (IN) | 2005-10-12 | — | — | EP | claimed |
| WO-2004056767-A1 | 1-SUBSTITUTED-3-PYRROLIDINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2004-07-08 | — | — | WO | claimed |
| CN-101175482-B | Abuse-proofed dosage form | GRUENENTHAL GMBH | 2013-09-18 | — | — | CN | disclosed |
| CN-101175482-A | Abuse-proofed dosage form | GRUENENTHAL GMBH (DE) | 2008-05-07 | — | — | CN | disclosed |