SCHEMBL6183511

SCHEMBL6183511

CC(C)c1cccc(C(C)C)c1NC(=O)N(Cc1ccc2oc(=O)[nH]c2c1)CC1(c2ccccn2)CCCCC1

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NMBR P28336 19/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6186309 0.83 NMBR (0.51) NMBR
SCHEMBL6803553 0.82 NMBR (0.50) NMBR
SCHEMBL6185222 0.82 NMBR (0.45) NMBR
SCHEMBL6183034 0.81 NMBR (0.48) NMBR
SCHEMBL6804233 0.81 NMBR (0.52) NMBR
SCHEMBL6805340 0.81 NMBR (0.48) NMBR
SCHEMBL6183621 0.80 NMBR (0.46) NMBR
SCHEMBL6185673 0.79 NMBR (0.45) NMBR
SCHEMBL6184290 0.79 NMBR (0.46) NMBR
SCHEMBL6182338 0.79 NMBR (0.47) NMBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1501800-A1 BOMBESIN ANTAGONISTS Warner-Lambert Company LLC (US) 2005-02-02 EP disclosed
US-20040063643-A1 Bombesin antagonists PFIZER INC. 2004-04-01 US disclosed
WO-2003092670-A1 BOMBESIN ANTAGONISTS WARNER-LAMBERT COMPANY LLC (US) 2003-11-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063643-A1 Bombesin antagonists BRS3, NPSR1, GNRHR NMBR 211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.