Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 14/20 | 0.66 |
| ▸ | ACACA | Q13085 | 14/20 | 0.66 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3465253 | 0.94 | ACACB (0.74) | ACACBACACAKDM2BGAA | |
| SCHEMBL6183390 | 0.94 | ACACB (0.74) | ACACBACACAKDM2BGAA | |
| SCHEMBL27596430 | 0.87 | ACACB (0.69) | ACACBACACA | |
| Diethylamine SCHEMBL7108528 | 0.87 | ACACB (0.71) | ACACBACACAKDM2B | |
| SCHEMBL6498280 | 0.84 | ACACB (0.91) | ACACBACACA | |
| SCHEMBL6183513 | 0.84 | ACACB (0.66) | ACACBACACAGAA | |
| SCHEMBL13953186 | 0.84 | ACACB (0.72) | ACACBACACAKDM2BGAA | |
| SCHEMBL6182395 | 0.84 | ACACB (0.72) | ACACBACACAKDM2BGAA | |
| SCHEMBL2622327 | 0.84 | ACACB (0.74) | ACACBACACAKDM2BGAA | |
| SCHEMBL6183505 | 0.83 | ACACB (0.84) | ACACBACACAKDM2BGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478437-B1 | ACC INHIBITORS | PFIZER PROD INC (US) | 2005-08-31 | — | — | EP | disclosed |
| CN-1642599-A | ACC inhibitors | PFIZER PROD INC (US) | 2005-07-20 | — | — | CN | disclosed |