Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7815898 | 0.99 | SCN9A (0.35) | SCN9ACTNNB1WNT3AMRGPRX4KIF11 | |
| SCHEMBL7815894 | 0.88 | SCN9A (0.35) | SCN9ACTNNB1WNT3AKIF11ADORA2A | |
| SCHEMBL8816467 | 0.83 | CTNNB1 (0.38) | CTNNB1WNT3AMRGPRX4ADORA2AHDAC4 | |
| SCHEMBL6182417 | 0.80 | SCN9A (0.33) | SCN9A | |
| SCHEMBL6182206 | 0.75 | DHODH (0.32) | SCN9A | |
| SCHEMBL3800470 | 0.75 | CTNNB1 (0.37) | SCN9ACTNNB1WNT3AMRGPRX4ADORA2A | |
| SCHEMBL6183673 | 0.75 | AOC3 (0.45) | CTNNB1 | |
| SCHEMBL6182117 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL7817921 | 0.74 | AOC3 (0.44) | CTNNB1 | |
| SCHEMBL22209012 | 0.73 | CTNNB1 (0.38) | SCN9ACTNNB1WNT3AMRGPRX4ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160244-B1 | Isoxazole derivatives and their use as herbicides | BAYER AGRICULTURE LTD (GB) | 2005-10-19 | — | — | EP | disclosed |
| EP-1160244-A1 | Isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-12-05 | — | — | EP | disclosed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | disclosed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |