Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183370 | 0.92 | — | — | |
| SCHEMBL6183964 | 0.86 | EDNRA (0.37) | EDNRANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9079156 | 0.84 | AOC3 (0.35) | EDNRA | |
| SCHEMBL6182679 | 0.83 | SYK (0.30) | — | |
| SCHEMBL9118267 | 0.83 | EDNRA (0.37) | EDNRA | |
| SCHEMBL6185334 | 0.81 | EDNRA (0.33) | EDNRA | |
| SCHEMBL9239343 | 0.78 | HPGD (0.32) | NPC1POLBMAPTNFKB1RAB9A | |
| SCHEMBL6441376 | 0.76 | — | — | |
| SCHEMBL9118511 | 0.76 | EDNRA (0.45) | EDNRANPC1POLBNFKB1RAB9A | |
| SCHEMBL9195406 | 0.74 | HPGD (0.37) | NPC1MAPTNFKB1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160244-B1 | Isoxazole derivatives and their use as herbicides | BAYER AGRICULTURE LTD (GB) | 2005-10-19 | — | — | EP | disclosed |
| EP-1160244-A1 | Isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-12-05 | — | — | EP | disclosed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | disclosed |
| WO-1995025099-A1 | 2-CYANO-1,3-DIONE DERIVATIVES USEFUL AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-09-21 | — | — | WO | disclosed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |