Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6182823 | 0.86 | GSK3B (0.59) | GSK3BCDK2 | |
| SCHEMBL6069213 | 0.86 | GSK3B (0.65) | GSK3BCDK2 | |
| SCHEMBL6184717 | 0.84 | GSK3B (0.56) | GSK3BCDK2 | |
| SCHEMBL5890649 | 0.81 | CSNK1D (0.51) | GSK3B | |
| SCHEMBL4479248 | 0.79 | GSK3B (1.00) | GSK3BCDK2 | |
| Gw833373X SCHEMBL4480568 | 0.77 | GSK3B (1.00) | GSK3BCDK2 | |
| SCHEMBL6183945 | 0.77 | GSK3B (0.61) | GSK3BCDK2 | |
| SCHEMBL5453810 | 0.76 | GSK3B (0.59) | GSK3BCDK2 | |
| SCHEMBL5890227 | 0.76 | CSNK1D (0.49) | GSK3B | |
| Gw829055X SCHEMBL4489350 | 0.75 | GSK3B (1.00) | GSK3BCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341788-B1 | PYRAZOLOPYRIDINES | GLAXO GROUP LTD (GB) | 2005-08-10 | — | — | EP | disclosed |
| US-6919352-B2 | Pyrazolopyridinyl pyridine and pyrimidine therapeutic compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2005-07-19 | — | — | US | disclosed |
| US-20040072853-A1 | Therapeutic compounds | CHAMBERLAIN STANLEY D (US) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072853-A1 | Therapeutic compounds | PCSK9, ABCB1, FURIN | GSK3B 1270/4885CDK2 1885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.