Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 15/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6032430 | 0.75 | MAPK1 (0.31) | MAPK1 | |
| SCHEMBL21610740 | 0.75 | MAPK1 (0.40) | MAPK1 | |
| SCHEMBL22549094 | 0.74 | MAPK1 (0.31) | MAPK1 | |
| SCHEMBL21610738 | 0.73 | MAPK1 (0.38) | MAPK1 | |
| SCHEMBL12869685 | 0.72 | MAPK1 (0.34) | MAPK1 | |
| SCHEMBL2389630 | 0.71 | MAPK1 (0.33) | MAPK1 | |
| Hydrochloric Acid SCHEMBL1173700 | 0.70 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL6182182 | 0.70 | MAPK1 (0.37) | MAPK1 | |
| SCHEMBL21610732 | 0.69 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL15888824 | 0.69 | MAPK1 (0.33) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920424-B1 | NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 2005-11-30 | — | — | EP | disclosed |
| US-6194437-B1 | ANTIDEPRESSANTS; ANTICANCER AGENTS; GASTROINTESTINAL DISORDERS; COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY | 2001-02-27 | — | — | US | disclosed |
| EP-0920424-A1 | NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998007718-A1 | NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-02-26 | — | — | WO | disclosed |