Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 19/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 17/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.64 |
| ▸ | NOS1 | P29475 | 1/20 | 0.59 |
| ▸ | NOS2 | P35228 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4495794 | 0.92 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3NOS1NOS2 | |
| Fumaric Acid SCHEMBL5997020 | 0.89 | SLC6A2 (0.72) | SLC6A2SLC6A4SLC6A3 | |
| Fumaric Acid SCHEMBL5997015 | 0.89 | SLC6A2 (0.72) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5993744 | 0.87 | SLC6A2 (0.75) | SLC6A2SLC6A4SLC6A3NOS1NOS2 | |
| SCHEMBL5994994 | 0.86 | SLC6A2 (0.77) | SLC6A2SLC6A4SLC6A3NOS1NOS2 | |
| SCHEMBL5995526 | 0.84 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3 | |
| Cadaverine Tartrate SCHEMBL4486465 | 0.83 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3NOS1NOS2 | |
| SCHEMBL5995104 | 0.83 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5997705 | 0.82 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3NOS1NOS2 | |
| SCHEMBL5995299 | 0.82 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569905-A2 | INHIBITORS OF MONOAMINE UPTAKE | ELI LILLY AND COMPANY (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004052858-A2 | INHIBITORS OF MONOAMINE UPTAKE | ELI LILLY AND COMPANY (US) | 2004-06-24 | — | — | WO | disclosed |