⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060370 | 0.87 | TSHR (0.30) | — | |
| SCHEMBL11650478 | 0.84 | HSD17B10 (0.39) | — | |
| SCHEMBL9257876 | 0.78 | — | — | |
| SCHEMBL15223405 | 0.77 | — | — | |
| SCHEMBL22443266 | 0.77 | — | — | |
| SCHEMBL10314768 | 0.77 | — | — | |
| SCHEMBL10314771 | 0.77 | — | — | |
| SCHEMBL23287922 | 0.74 | — | — | |
| SCHEMBL16693297 | 0.74 | — | — | |
| SCHEMBL10204684 | 0.74 | SLC22A16 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900200-B9 | PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | TARGACEPT INC (US) | 2009-10-21 | — | — | EP | claimed |
| EP-0900200-B1 | PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | TARGACEPT INC (US) | 2008-12-03 | — | — | EP | claimed |
| US-6979695-B2 | Compounds capable of activating cholinergic receptors | TARGACEPT, INC. (US) | 2005-12-27 | — | — | US | claimed |
| EP-1086082-B9 | ARYLSUBSTITUTED OLEFINIC AMINES AND THEIR USE AS CHOLINERGIC RECEPTORS AGONISTS | TARGACEPT INC (US) | 2005-03-02 | — | — | EP | claimed |
| EP-1086082-B1 | ARYLSUBSTITUTED OLEFINIC AMINES AND THEIR USE AS CHOLINERGIC RECEPTORS AGONISTS | TARGACEPT INC (US) | 2004-08-18 | — | — | EP | claimed |
| US-20030125345-A1 | Nicotinic compounds; treating central nervous system disorders | TARGACEPT, INC. | 2003-07-03 | — | — | US | claimed |
| US-20250340502-A1 | PURIFICATION OF AN ETHYLENICALLY UNSATURATED ALCOHOL STREAM, PREPARATION OF AN ETHYLENICALLY UNSATURATED ALDEHYDE, IN PARTICULAR PRENAL, AND COMPOUNDS DERIVED THEREFROM | BASF SE (DE) | 2025-11-06 | — | — | US | disclosed |
| CN-119278192-A | Purification of ethylenically unsaturated alcohol streams, preparation of ethylenically unsaturated aldehydes, in particular pentenals, and compounds derived therefrom | 巴斯夫欧洲公司 | 2025-01-07 | — | — | CN | disclosed |
| WO-2019165783-A1 | METHOD FOR CONTINUOUSLY PREPARING 2-METHYLALLYL PROPANATE ALCOHOL SOLUTION | 浙江大学 | 2019-09-06 | — | — | WO | disclosed |
| EP-2725422-B1 | PHOTOSENSITIVE COMPOSITION, MASTER PLATE FOR PLANOGRAPHIC PRINTING PLATE AND POLYURETHANE | FUJIFILM CORP (JP) | 2017-10-04 | — | — | EP | disclosed |
| US-20150313883-A1 | HYDROXYBENZOATE SALTS OF METANICOTINE COMPOUNDS | TARGACEPT INC (US) | 2015-11-05 | — | — | US | disclosed |
| EP-2257514-B1 | METHOD FOR PRODUCING OLEFINICALLY SATURATED CARBONYL COMPOUNDS BY OXIDATIVE DEHYDROGENATION OF ALCOHOLS | BASF SE (DE) | 2015-10-28 | — | — | EP | disclosed |
| US-9107915-B2 | Hydroxybenzoate salts of metanicotine compounds | TARGACEPT, INC. (US) | 2015-08-18 | — | — | US | disclosed |
| WO-1999065876-A1 | ARYL SUBSTITUTED OLEFINIC AMINES AND THEIR USE AS CHOLINERGIC RECEPTORS AGONISTS | R.J. REYNOLDS TOBACCO COMPANY (US) | 1999-12-23 | — | — | WO | disclosed |
| WO-1999043322-A1 | METHOD FOR THE TREATMENT OF PAIN, INCLUDING CHRONIC AND FEMALE SPECIFIC PAIN | WAKE FOREST UNIVERSITY (US) | 1999-09-02 | — | — | WO | disclosed |
| EP-0900200-A1 | PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | R.J. REYNOLDS TOBACCO COMPANY (US) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997040011-A1 | PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | R. J. REYNOLDS TOBACCO COMPANY (US) | 1997-10-30 | — | — | WO | disclosed |
| US-5616716-A | (3-(5-ethoxypyridin)yl)-alkenyl 1 amine compounds | TARGACEPT, INC. | 1997-04-01 | — | — | US | disclosed |
| US-4883913-A | BUT-3-EN-1-OL COMPOUNDS, MIXTURES OF CATALYSTS AND BLOWING AGENTS FOR POLYURETHANES | KALI-CHEMIE AKTIENGESELLSCHAFT (DE) | 1989-11-28 | — | — | US | disclosed |
| US-4111917-A | POLYURETHANES | W. R. GRACE & CO. (US) | 1978-09-05 | — | — | US | disclosed |