⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6136792 | 0.59 | — | — | |
| SCHEMBL901607 | 0.59 | — | — | |
| SCHEMBL19096 | 0.58 | — | — | |
| SCHEMBL294948 | 0.56 | — | — | |
| SCHEMBL133547 | 0.56 | — | — | |
| SCHEMBL9387971 | 0.56 | — | — | |
| SCHEMBL10948500 | 0.56 | — | — | |
| SCHEMBL693933 | 0.56 | — | — | |
| Hydrochloric Acid SCHEMBL10661119 | 0.50 | — | — | |
| SCHEMBL11569584 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349860-B1 | SYNTHESES FOR PREPARING 1,4-DIKETOPYRROLO[3,4-C]PYRROLES | SUN CHEMICAL CORP (US) | 2004-08-18 | — | — | EP | claimed |
| EP-1349860-A2 | SYNTHESES FOR PREPARING 1,4-DIKETOPYRROLO[3,4-C]PYRROLES | SUN CHEMICAL CORPORATION (US) | 2003-10-08 | — | — | EP | claimed |
| WO-2002068422-A2 | SYNTHESES FOR PREPARING 1,4-DIKETOPYRROLO[3,4-C]PYRROLES | SUN CHEMICAL CORPORATION (US) | 2002-09-06 | — | — | WO | claimed |
| US-6388093-B1 | REACTING A B-KETOAMIDE WITH A STRONG BASE; HALOGENTAION; CYCLIZATION | SUN CHEMICAL CORPORATION | 2002-05-14 | — | — | US | claimed |
| US-9969742-B2 | Imidazotriazinone compounds | IRONWOOD PHARMACEUTICALS, INC. (US) | 2018-05-15 | — | — | US | disclosed |
| US-20170327502-A1 | IMIDAZOTRIAZINONE COMPOUNDS | IRONWOOD PHARMACEUTICALS INC (US) | 2017-11-16 | — | — | US | disclosed |
| US-9725453-B2 | Imidazotriazinone compounds | IRONWOOD PHARMACEUTICALS, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| US-20150191476-A1 | Imidazotriazinone Compounds | FORUM PHARMACEUTICALS INC. | 2015-07-09 | — | — | US | disclosed |
| EP-2828262-A1 | IMIDAZOTRIAZINONE COMPOUNDS | Forum Pharmaceuticals Inc. (US) | 2015-01-28 | — | — | EP | disclosed |
| WO-2013142269-A1 | IMIDAZOTRIAZINONE COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. (US) | 2013-09-26 | — | — | WO | disclosed |
| EP-1273582-B1 | Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents | PFIZER PROD INC (US) | 2005-06-29 | — | — | EP | disclosed |
| US-6900230-B2 | Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents | PFIZER INC. (US) | 2005-05-31 | — | — | US | disclosed |
| US-20030119836-A1 | Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents | SAKYA SUBAS M (US) | 2003-06-26 | — | — | US | disclosed |
| EP-1273582-A1 | Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents | Pfizer Products Inc. (US) | 2003-01-08 | — | — | EP | disclosed |