Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6185364 | 0.97 | KDM4E (0.46) | HRH1KDM4EMAOB | |
| SCHEMBL6187276 | 0.95 | HRH1 (0.45) | HRH1KDM4EMAOBTSHR | |
| SCHEMBL6186189 | 0.95 | HRH1 (0.45) | HRH1KDM4EMAOBTSHR | |
| SCHEMBL6187569 | 0.94 | HRH1 (0.53) | HRH1KDM4EMAOBTSHR | |
| SCHEMBL6184768 | 0.90 | TSHR (0.44) | HRH1KDM4EMAOBTSHR | |
| SCHEMBL6182314 | 0.85 | TSHR (0.45) | HRH1KDM4EMAOBTSHR | |
| SCHEMBL6185574 | 0.83 | HRH1 (0.52) | HRH1KDM4E | |
| SCHEMBL6185121 | 0.83 | ABCB1 (0.49) | HRH1KDM4E | |
| SCHEMBL6185078 | 0.82 | PPARG (0.53) | — | |
| SCHEMBL6185937 | 0.81 | DRD1 (0.51) | KDM4EMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1275641-B1 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-01-12 | — | — | EP | disclosed |
| US-6541471-B1 | Useful as a TXA2 receptor antagonist and a 5-HT2 receptor antagonist | LES LABORATOIRES SERVIER (FR) | 2003-04-01 | — | — | US | disclosed |
| EP-1275641-A2 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2003-01-15 | — | — | EP | disclosed |