Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.40 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798348 | 0.82 | SOAT1 (0.40) | SOAT1SOAT2UBE2MDCUN1D1ACAT1 | |
| SCHEMBL6184255 | 0.80 | SOAT1 (0.42) | SOAT1SOAT2UBE2MDCUN1D1ACAT1 | |
| SCHEMBL6182575 | 0.80 | SOAT1 (0.42) | SOAT1SOAT2UBE2MDCUN1D1ACAT1 | |
| SCHEMBL6183404 | 0.79 | LPAR1 (0.42) | SOAT1SOAT2UBE2MDCUN1D1ACAT1 | |
| SCHEMBL6202938 | 0.78 | SOAT1 (0.40) | SOAT1SOAT2UBE2MDCUN1D1ACAT1 | |
| SCHEMBL6183730 | 0.78 | SOAT1 (0.42) | SOAT1SOAT2UBE2MDCUN1D1ACAT1 | |
| SCHEMBL6186309 | 0.78 | NMBR (0.51) | SOAT1SOAT2ACAT1 | |
| SCHEMBL6807653 | 0.77 | SOAT1 (0.43) | SOAT1SOAT2UBE2MDCUN1D1ACAT1 | |
| SCHEMBL6184564 | 0.77 | SOAT1 (0.41) | SOAT1SOAT2UBE2MDCUN1D1ACAT1 | |
| SCHEMBL6803816 | 0.77 | SOAT1 (0.49) | SOAT1SOAT2ACAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501800-A1 | BOMBESIN ANTAGONISTS | Warner-Lambert Company LLC (US) | 2005-02-02 | — | — | EP | claimed |
| US-20040063643-A1 | Bombesin antagonists | PFIZER INC. | 2004-04-01 | — | — | US | claimed |
| WO-2003092670-A1 | BOMBESIN ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2003-11-13 | — | — | WO | claimed |
| EP-1501800-A1 | BOMBESIN ANTAGONISTS | Warner-Lambert Company LLC (US) | 2005-02-02 | — | — | EP | disclosed |
| US-20040063643-A1 | Bombesin antagonists | PFIZER INC. | 2004-04-01 | — | — | US | disclosed |
| WO-2003092670-A1 | BOMBESIN ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | BRS3, NPSR1, GNRHR | NLRP3 881/4885SOAT1 3334/4885SOAT2 3379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.