SCHEMBL6185637

SCHEMBL6185637

CC(=O)O[C@H]1CCc2cc(OCCc3nc(-c4ccc(C)c(NCc5ccccc5)c4)oc3C)ccc21

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.57
PPARA Q07869 17/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4452708 0.88 PPARG (0.75) PPARGPPARA
SCHEMBL4455716 0.86 PPARG (0.75) PPARGPPARA
SCHEMBL4682395 0.86 PPARG (0.70) PPARGPPARA
SCHEMBL4679074 0.86 PPARG (0.74) PPARGPPARA
SCHEMBL4680793 0.86 PPARG (0.73) PPARGPPARA
SCHEMBL4686016 0.86 PPARG (0.70) PPARGPPARA
SCHEMBL13958896 0.85 PPARG (0.65) PPARGPPARA
SCHEMBL4682995 0.85 PPARA (0.71) PPARGPPARA
SCHEMBL6188513 0.84 PPARG (0.60) PPARGPPARA
SCHEMBL4678922 0.83 PPARA (0.72) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1497271-A1 INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS Bayer Pharmaceuticals Corporation (US) 2005-01-19 EP disclosed
WO-2003089418-A1 INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS BAYER PHARMACEUTICALS CORPORATION (US) 2003-10-30 WO disclosed