⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9639739 | 0.69 | — | — | |
| SCHEMBL9639731 | 0.69 | — | — | |
| SCHEMBL11759040 | 0.69 | — | — | |
| SCHEMBL6963488 | 0.69 | — | — | |
| SCHEMBL6963480 | 0.69 | — | — | |
| SCHEMBL27541618 | 0.67 | — | — | |
| SCHEMBL11760867 | 0.65 | — | — | |
| SCHEMBL17351848 | 0.65 | — | — | |
| SCHEMBL11760871 | 0.65 | — | — | |
| SCHEMBL4651556 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572688-A1 | OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | Astrazeneca AB (SE) | 2005-09-14 | — | — | EP | disclosed |
| EP-1446403-A1 | ARYL SUBSTITUTED OXAZOLIDINONES WITH ANTIBACTERIAL ACTIVITY | AstraZeneca AB (SE) | 2004-08-18 | — | — | EP | disclosed |
| EP-1443930-A1 | ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | AstraZeneca AB (SE) | 2004-08-11 | — | — | EP | disclosed |
| WO-2004056817-A1 | OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2004-07-08 | — | — | WO | disclosed |
| EP-1427711-A1 | OXAZOLIDINONE AND/OR ISOXAZOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | AstraZeneca AB (SE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003035073-A1 | ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | ASTRAZENECA AB (SE) | 2003-05-01 | — | — | WO | disclosed |
| WO-2003035648-A1 | ARYL SUBSTITUTED OXAZOLIDINONES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2003-05-01 | — | — | WO | disclosed |
| WO-2003022824-A1 | OXAZOLIDINONE AND/OR ISOXAZOLINE AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2003-03-20 | — | — | WO | disclosed |